Study reveals sugar-filled soda ages you just like smoking does

10 years ago | Posted in: Health | 614 Views

Before you crack that next can of soda, you might want to think again. The results are in on a study that followed 5,309 adults for 14 years to see what, if any effect drinking sugary soda had on aging. The study conducted by University of California professor Elissa Epel indicates that high sugar consumption may result in increased aging in the same way regular smoking does.

After analyzing the data, researchers found that people who drank one 8-oz serving per day (i.e. less than a standard 12-oz can) resulted in 1.9 years of additional aging. Consuming 20-oz each day caused about 4.6 extra years of aging, which the authors are keen to point out is the same seen in studies of smoking. Epel arrived at these estimates by tracking the length of telomeres in the participants’ cells.

A telomere is a region of repeating nucleic acid at the end of each chromosome (the white caps below) in the nucleus of your cells. It’s basically extra DNA that doesn’t code for anything and is attached to your important DNA–the stuff that codes for proteins needed to run your cells. The purpose of a telomere is to buffer your genes against loss from the dense environment inside the cell, and also when DNA is replicated. It really all comes down to cell division (mitosis), which is what keeps the biological machine going. You can probably guess how this relates to aging.

Every time one of your cells divides, it needs a complete copy of the nuclear genome. The enzymes that make copies of each chromosome can’t get all the way to the end of a strand of DNA, so a little snippet is lost. That’s why telomeres are there. You lose a bit of the telomere instead of an important segment of DNA. As cells divide again and again, the telomeres get shorter until they can no longer protect the DNA, and a cell stops dividing. This is called the Hayflick limit.

Researchers have long postulated that shortening telomeres are associated with aging, thus the interest in studying how different substances affect them. In this case, the sugar in soda appears to be the main culprit. When comparing diet soda to a control in the study, researchers found no statistically significant difference in telomere length. So it seems that high sugar intake could be affecting the metabolism of cells in a negative way–possibly accelerating mitosis in some fashion… see more

source: geek

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