A US drone fired two missiles at a vehicle in northwest Pakistan, killing four suspected insurgents on Saturday, Pakistani intelligence officials said.
The attack took place in Mohammed Khel village in the North Waziristan tribal region bordering Afghanistan, the officials told the Associated Press (AP).
Officials said that the identities of those killed were not immediately known and their agents are trying to get more details.
They spoke to AP on condition of anonymity because they were not authorised to speak to reporters.
The attack comes as Pakistan renewed demands to halt missile operations in the country.
Pakistan President Asif Ali Zardari met with US special envoy to the region Marc Grossman six days ago and told him the US must put an end to the strikes, describing them as counterproductive to the fight against militancy.